Thirty-Second Bunnies Theater
AOOA is an odd, odd little Flash game. You need a high-speed connection or a lot of patience, or both.
Tales of Future Past. I know I've mentioned them before, but they rock so they get another mention.
The Chronicles of George, more tales of tech support
KEMONO STUDIO, some very neat fursuits from Japan
Albinoblacksheep, one of the best places for silly Flash stuff
Today In Alternate History
8legged.com, the home of Tako the Octopus. Great Flash animations about cooking. Really.
Colonel Blimp, a pro music video production company that has some very cool Quicktime files